Yazar "Serdaroğlu, Goncagül" için listeleme
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Carbazole derivatives: Synthesis, spectroscopic characterization, antioxidant activity, molecular docking study, and the quantum chemical calculations
Serdaroğlu, Goncagül; Uludağ, Nesimi; Erçağ, Erol; Sugumar, Paramasivam; Rajkumar, Parthasarathi (Elsevier, 2021)A various carbazole derivativeswere synthesized for the synthesis 2,3-Dihydro-1H-carbazol-4(9H)-one O-acetyl oxime (3), ethyl 2-(2,3,4,9-tetrahydrospiro[carbazole-1,2'-[1,3]dithiolane]-2-yl)acetate (5), 2- hydroxyethyl ... -
Concise total synthesis of (+/-)-aspidospermidine and computational study: FT-IR, NMR, NBO, NLO, FMO, MEP diagrams
Serdaroğlu, Goncagül; Uludağ, Nesimi (Elsevier, 2018)Aspidospermidine is a member of the compound class known as aspidospermaten-type alkaloids. Aspidospermidine is among the most highly sought aspidosperma alkaloid targets because it comprises the basic skeletal features ... -
Cyanomethylation of 2,3,4,9-tetrahydro-1H-carbazol-1-one based on using two different reagents: Antioxidant activity and DFT studies
Serdaroğlu, Goncagül; Uludağ, Nesimi; Erçağ, Erol (Elsevier, 2022)C-2 and C-6 monoalkyl nitrile substituted reactant (1), which constitute the tricyclic framework of carbazole derivatives along with the substructure of the Strychnos alkaloids family, have been synthesized by using different ... -
A DFT Investigation on the Structure, Spectroscopy (FT-IR and NMR), Donor-Acceptor Interactions and Non-Linear Optic Properties of (+/-)-1,2-Dehydroaspidospermidine
Uludağ, Nesimi; Serdaroğlu, Goncagül (Wiley-V C H Verlag Gmbh, 2019)In this study, (+/-)-1,2-Dehydroaspidospermidine was analyzed by elemental analysis, H-1 and C-13 NMR, and FT-IR spectra. Also, because the starting geometry is essential to evaluate the structural, electronic, and spectral ... -
An efficient method for the azocino[4,3-b]indole framework of strychnos alkaloids: OFT investigations on the electronic and spectroscopic properties
Uludağ, Nesimi; Serdaroğlu, Goncagül; Çolak, Naki (Scientific Publ-India, 2019)Tetracyclic 1,5-methanoazocino[4,3-b]indole (2) was achieved via a new synthetic approach for the synthesis of related strychnos alkaloids. These products embody the ABCD-ring system associated with the title alkaloids, ... -
An efficient studies on C-2 cyanomethylation of the indole synthesis: the electronic and spectroscopic characterization (FT-IR, NMR, UV-Vis), antioxidant activity, and theoretical calculations
Uludağ, Nesimi; Serdaroğlu, Goncagül (Elsevier, 2022)The direct cynamethylation with the development of catalyzed methodologies directed to 2-(cyanomethyl)indoles was reported by using tetrafluoro-1,4-benzoquinone (TFB) as the catalyst and it was synthesized in one step ... -
The electronic and spectroscopic investigation of ( +/- )- Dasycarpidone
Serdaroğlu, Goncagül; Uludağ, Nesimi (Elsevier, 2020)(+/-)-Dasycarpidone ((1R,5S)-12-ethyl-2-methyl-1,2,3,4,5,7-hexahydro-6H-1,5-methanoazocino[4,3-b]indol-6one) was investigated by using the quantum chemical calculations. All DFT-based analyses were performed by B3LYP, ... -
An entry to the synthesis of uleine-type alkaloids by Fischer indole synthesis reactions: FT-IR, NMR spectroscopy and computational study of the substituted carbazole compound
Serdaroğlu, Goncagül; Uludağ, Nesimi (Bulgarian Academy of Sciences, 2018)An efficient and straightforward method for the synthesis of 2-(2,3,4,9-tetrahydro-1H-carbazole-2-yl)acetonitrile by Fischer reaction of phenylhydrazine hydrochloride acid and 2-(3-oxocyclohexyl)acetonitrile in presence ... -
An improved synthesis, spectroscopic (FT-IR, NMR) study and DFT computational analysis (IR, NMR, UV-Vis, MEP diagrams, NBO, NLO, FMO) of the 1,5-methanoazocino[4,3-b]indole core structure
Uludağ, Nesimi; Serdaroğlu, Goncagül (Elsevier, 2018)This study examines the synthesis of azocino[4,3-b]indole structure, which constitutes the tetracyclic framework of uleine, dasycarpidoneand tubifolidineas well as ABDE substructure of the strychnosalkaloid family. It has ... -
New route for synthesis of 2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b] indole and DFT investigation
Uludağ, Nesimi; Serdaroğlu, Goncagül (Elsevier Sci Ltd, 2020)Development of efficient sequences for the synthesis of the title compound (2-(2,2-dimethoxyethyl)-1,2,3,4,5,6-hexahydro-1,5-methanoazocino[4,3-b]indole) (7) was described. The title compound was synthesized through several ... -
Nitrobenzamido substitution on thiophene-3-carboxylate: Electrochemical investigation, antioxidant activity, molecular docking, DFT calculations
Serdaroğlu, Goncagül; Uludağ, Nesimi; Çolak, Naki; Rajkumar, Parthasarathi (Elsevier, 2023)A novel nitro containing thiophene derivatives containing have been synthesized. In pharmaceutical chemistry, thiophene derivatives show a biological effect. Due to the promising antimicrobial, analgesic and anti-inflammatory, ... -
A novel synthesis of octahydropyrido[3,2-c]carbazole framework of aspidospermidine alkaloids and a combined computational, FT-IR, NMR, NBO, NLO, FMO, MEP study of the cis-4a-Ethyl-1(2hydroxyethyl)-2,3,4,4a,5,6,7,11c-octahydro-1H-pyrido[3,2-c] carbazole
Uludağ, Nesimi; Serdaroğlu, Goncagül; Yinanç, Abdullah (Elsevier, 2018)In this study, we performed a novel synthesis of the octahydropyrido[3,2-c]carbazole derivative 6 from 1 in five steps with a 34% overall yield. We also developed a unique compound 2 by a cyclization reaction from the ... -
Spectroscopic (FT-IR, NMR) and Computational Investigation of 2-(2-Aminoethyl)-1,2,3,4,9-Tetrahydrocarbazole: NBO, NLO, FMO, MEP Analysis
Serdaroğlu, Goncagül; Uludağ, Nesimi (Pleiades Publishing Inc, 2019)The FT-IR, H-1 and C-13 NMR spectroscopic characterization of the title molecule is assessed by quantum chemical simulations in detail and compared with the observed values. First, the possible structures of the substituted ... -
Structural, electronic, and spectroscopic study on 1,5-methanoazocino[4,3-b]indole synthesized by TFB-based route
Serdaroğlu, Goncagül; Uludağ, Nesimi (Springer International Publishing Ag, 2021)This work proposed a new route to synthesizing pharmaceutical important molecules just in three steps. This synthetic route provides an economical way for synthetic chemistry to get the key products concerning the biochemical ... -
Strychnos alkaloids: total synthesis, characterization, DFT investigations, and molecular docking with AChE, BuChE, and HSA
Uludağ, Nesimi; Üstun, Elvan; Serdaroğlu, Goncagül (Elsevier Sci Ltd, 2022)An efficient five steps, the protection-deprotection synthetic a novel synthetic routes to(+/-) noruleine (f)-uleine, are reported starting from tetrahydrocarbazole fused monoalkyl nitrile at C-2 position that is prepared ... -
The synthesis and spectroscopic characterization of (+)-demethoxyaspidospermine: Density functional theory calculations of the structural, electronic, and non-linear optic and spectroscopic properties
Serdaroğlu, Goncagül; Uludağ, Nesimi (SAGE Publications Ltd, 2019)(+)-Demethoxyaspidospermine was synthesized via the acylation of aspidospermidine with acetic anhydride, and the structure was determined by elemental analysis and Fourier-transform infrared and nuclear magnetic resonance ... -
Synthesis of thiophene derivatives: Substituent effect, antioxidant activity, cyclic voltammetry, molecular docking, DFT, and TD-DFT calculations
Uludağ, Nesimi; Serdaroğlu, Goncagül; Sugumar, Paramasivam; Rajkumar, Parthasarathi; Çolak, Naki; Erçağ, Erol (Elsevier, 2022)The efficient pathway 6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate derivatives have been synthesized. Due to the promising biochemical reactivity, the bioactive agent synthesis in the frame of the thiophene ...